Importance of Disconnected Pancreatic Duct Syndrome in Recurrence of Pancreatic Fluid Collections Initially Drained Using Lumen-Apposing Metal Stents

Background & AimsIndwelling plastic endoprosthesis in patients with disconnected pancreatic duct syndrome (DPDS) reduces the risk of fluid collection (PFC) recurrence. Although lumen-apposing metal stents (LAMS) are used increasing frequency for PFC drainage, they require timely removal and little is known about their effects DPDS recurrence PFC.MethodsWe performed a prospective study who underwent endoscopic ultrasound-guided drainage using LAMS were found to have DPDS. After resolution PFC, replaced double-pigtail stents. The primary outcome was compare between did vs not receive replacements after LAMS.ResultsOf 188 treated LAMS, 94 had DPDS, 71 intact ducts, patency unknown 23. In replacement successful 70 (74.5%) technically unsuccessful 24 (25.5%). At median follow up 183 days (interquartile range, 179–188 days), although none an 7 (7.4%) (P = .020). recurred 1 whom stent (1.4%) 6 (25.0%) .001).ConclusionsIn treatment PFCs it important replace indwelling minimize reduce morbidity. Clinicaltrials.gov no: NCT02422095 Indwelling PFC. We LAMS. Of .001).